Figure 5 | Scientific Reports

Figure 5

From: Macrothrombocytopenia of Takenouchi-Kosaki syndrome is ameliorated by CDC42 specific- and lipidation inhibitors in MEG-01 cells

Figure 5

Abnormal colocalization of β-tubulin with F-actin in MK protrusions by Y64C expression. (a) Representative images of YFP-tagged cdc42- or YFP-expressing MEG-01 cells stained for F-actin (yellow), β-tubulin (red), and DAPI (blue) after 7-day culture in the presence of VPA. White squares indicate the magnified zone. (b) Line scans of F-actin (yellow) and β-tubulin (red) fluorescence intensity along the white line from a representative image from a. Scale bar: 10 μm.

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