Figure 4 | Scientific Reports

Figure 4

From: The gene repertoire of the main cysteine protease of Trypanosoma cruzi, cruzipain, reveals four sub-types with distinct active sites

Figure 4

Representation of the syntenic cruzipain clusters in T. cruzi chromosomes. The homologous chromosomes of the Dm28c and YC6 strains are identical and represented once, while for the hybrid CL Brener strain, the two alleles corresponding to the Esmeraldo-like (EL) and non-Esmeraldo-like (NEL) haplotypes are represented separately. In each cluster, cruzipain copies are shown as white arrows, numbered according to the sub-type to which they belong, while truncated cruzipain copies are shown as white rectangles. The cruzipain clusters of the YC6 strain are found on chromosome 35 (Chr 35), and on chromosome 6 (Chr 6) for CL Brener. Genes are represented from 5’ to 3’ (genomic), and the arrows point in the predicted transcription direction. The genomic sequences were manually curated to search for full length and truncated copies that are represented here and might not match current annotation of cruzipain genes in TriTrypDB.

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