Figure 4 | Scientific Reports

Figure 4

From: Construction of transplantable artificial vascular tissue based on adipose tissue-derived mesenchymal stromal cells by a cell coating and cryopreservation technique

Figure 4

Ultrastructure of perivascularly localized hASCs in ASCVT. (a) Electron micrograph of ASCVT. V: vascular structure constructed by HUVECs (red-colored). Interendothelial connecting junctions are observed (red arrows). Perivascularly localized hASCs are also shown. ECM: extracellular matrix. (b) High magnified image of hatched box in (a). The projections from hASC interact with HUVEC, suggesting the formation of peg-socket structure (yellow arrow). Inset shows further high magnified image of red hatched box containing caveola at cytoplasmic membrane. (c) Another high magnified image of hatched box in (a). The cytoplasm of perivascular hASCs shows filamentous structure that is considered as presence of actin filaments. Inset shows further high magnified image of red hatched box on cytoplasm. (d) The image of hASCs locate far from vascular structures. The cytoplasm shows the fibroblast-like structure with abundant rough endoplasmic reticulum (rER) and mitochondria (mt). The images are representatives from three independent experiments.

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