Table 1 Affinity constants for tested Z variants from SPR.
From: Discovery, optimization and biodistribution of an Affibody molecule for imaging of CD69
Tested Z variant in the format H6-ZCD69:#-(G4S)3-ABD | Kd (nM) | ||
|---|---|---|---|
vs. hCD69 | vs. mCD69 | vs. HSA | |
ZCD69:2 | 52 | 67 | 0.27 |
ZCD69:4 | 34 | 34 | 0.17 |
ZCD69:6 | 51 | 46 | 0.09 |
ZCD69:8 | 49 | ND | 0.49 |
ZCD69:10 | 29 | ND | 0.78 |
ZCD69:12 | 30 | ND | 0.52 |
