Table 3 Histopathological ischemic brain changes in rats.
Group | Dose | n | Histopathological grading of ischemic brain in rats | |||||
|---|---|---|---|---|---|---|---|---|
− | + | ++ | +++ | ++++ | P value | |||
Sham operation group | – | 6 | 6 | 0 | 0 | 0 | 0 | 0.002** |
Model group | – | 6 | 0 | 0 | 4 | 2 | 0 | 1.000 |
Nimodipine injection group | 0.5 mg/kg | 6 | 3 | 2 | 0 | 1 | 0 | 0.031* |
E. breviscapus injection group | 5 mL/kg/d | 6 | 1 | 4 | 0 | 1 | 0 | 0.030* |
Scutellarin group | 1.1505 mg/kg | 6 | 2 | 1 | 3 | 0 | 0 | 0.031* |
3,5-Dicaffeoylquinic acid group | 0.2335 mg/kg | 6 | 3 | 1 | 2 | 0 | 0 | 0.016* |
