Table 1 Clinical characteristics of the participants.

From: Effect of cryoprecipitate transfusion therapy in patients with postpartum hemorrhage: a retrospective cohort study

Variable

N

Overall, N = 1571

Control group, N = 1191

CRYO group, N = 381

p-value2

Age, yrs

157

34 (30, 37)

34 (30, 37)

34 (30, 38)

0.632

Gestational age, wk

155

39.14 (37.71, 40.29)

39.29 (37.86, 40.29)

38.57 (37.43, 39.86)

0.276

Parity

153

   

0.940

1

 

93 (60.8%)

72 (61.5%)

21 (58.3%)

 

2

 

42 (27.5%)

31 (26.5%)

11 (30.6%)

 

3

 

17 (11.1%)

13 (11.1%)

4 (11.1%)

 

 > 4

 

1 (0.7%)

1 (0.9%)

0 (0%)

 

Singleton/multiple birth

157

   

0.200

Singleton

 

149 (94.9%)

38 (100.0%)

111 (93.3%)

 

Twin

 

8 (5.1%)

0 (0.0%)

8 (6.7%)

 

Mode of delivery

157

   

0.127

Vaginal delivery

 

96 (61.1%)

77 (64.7%)

19 (50.0%)

 

Caesarean section

 

61 (38.9%)

42 (35.3%)

19 (50.0%)

 

Transfer time, min

127

208.0 (115.0, 333.5)

222.0 (117.0, 335.0)

197.5 (95.8, 316.8)

0.489

Transfusion before arrival

157

31 (19.7%)

17 (14.3%)

14 (36.8%)

0.004

Using of ART

139

67 (48.2%)

54 (51.4%)

13 (38.2%)

0.236

Major pregnancy complications

156

12 (7.7%)

6 (5.1%)

6 (15.8%)

0.072

Lactate, mg/dL

153

25.0 (17.0, 34.0)

23.0 (15.0, 31.2)

30.0 (21.0, 40.0)

0.009

Hemoglobin, g/dL

157

7.4 (6.0, 9.3)

7.6 (6.3, 9.4)

6.6 (5.2, 8.0)

0.026

Fibrinogen, mg/dL

155

183.0 (136.5, 265.5)

214.0 (150.0, 285.0)

140.0 (53.8, 178.8)

 < 0.001

PT-INR

153

1.1 (1.0, 1.2)

1.1 (1.0, 1.2)

1.2 (1.1, 1.4)

 < 0.001

Platelet count, × 103/μL

157

134.0 (104.0, 182.0)

140.0 (115.0, 193.5)

95.0 (49.0, 148.2)

 < 0.001

Body temperature, °C

157

36.7 (36.3, 37.1)

36.6 (36.3, 37.0)

36.8 (36.0, 37.2)

0.805

Shock Index

157

0.9 (0.7, 1.2)

0.9 (0.7, 1.2)

1.1 (0.8, 1.4)

0.038

APACHE II score, pts

156

11.0 (9.0, 14.0)

11.0 (9.0, 13.0)

13.0 (10.0, 18.0)

0.001

Clark’s criteria, pts

157

1.0 (0.0, 2.0)

0.0 (0.0, 1.0)

2.5 (1.0, 3.0)

 < 0.001

Number of patients who met Clark’s DIC criteria (≥ 3 scores)

157

29 (18.5%)

10 (8.4%)

19 (50.0%)

 < 0.001

Obstetrics DIC score, pts

156

6.0 (4.0, 9.0)

5.0 (3.0, 8.0)

9.0 (7.0, 12.0)

 < 0.001

Number of patients who met obstetrics DIC score (≥ 13 scores)

156

14 (9.0%)

5 (4.2%)

9 (23.7%)

0.001

  1. Major pregnancy complications include pregnancy hypertension syndrome, gestational diabetes, and abruptio placentae. Body temperature was recorded as the lowest body temperature during blood transfusion. Shock index was calculated as heart rate divided by systolic blood pressure.
  2. CRYO, cryoprecipitate; BMI, body mass index; ART, assisted reproductive technology; APACHE II score, Acute Physiology and Chronic Health Evaluation II score; DIC, disseminated intravascular coagulation.
  3. 1Statistical data are presented as the median (interquartile range) or n (%).
  4. 2Statistical tests performed: Wilcoxon rank-sum test; Fisher's exact test.
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