Table 1 Association between host factors and telomere dynamics during the controlled human malaria infection (n = 16,481 observations).
From: Biomarkers of cellular aging during a controlled human malaria infection
Parameters | Univariate analysis | Multivariate analysis | ||||||
|---|---|---|---|---|---|---|---|---|
Coef. | SE | Z | p-value | Coef. | SE | Z | p-value | |
Time | 0.023 | 0.008 | 2.71 | 0.007 | ||||
Time spline1 | − 0.053 | 0.024 | − 2.16 | 0.031 | ||||
Time spline 2 | 0.117 | 0.035 | 3.30 | 0.001 | ||||
Age (years) | − 0.255 | 0.236 | − 1.08 | 0.281 | − 0.369 | 0.224 | − 1.65 | 0.099 |
Female | 2.919 | 1.388 | 2.10 | 0.035 | 2.889 | 1.394 | 2.07 | 0.038 |
Weight (kg) | − 0.064 | 0.067 | − 0.95 | 0.343 | − 0.05 | 0.074 | − 0.68 | 0.499 |
Treatment | − 0.461 | 0.604 | − 0.76 | 0.446 | − 0.601 | 0.624 | − 0.96 | 0.335 |