Figure 6 | Scientific Reports

Figure 6

From: Inflammatory signature in acute-on-chronic liver failure includes increased expression of granulocyte genes ELANE, MPO and CD177

Figure 6

Comparative analysis of ACLF PMN DEG from our dataset with published eosinophil DEG from hypereosinophilia patients versus healthy controls and with recently published ACLF neutrophil DEG. (A) 11 of 3177 (0.34%) genes were common between ACLF versus HC (our dataset) and Eosinophil versus HC and 12 of 2068 genes (0.58%) were common between ACLF versus CLD (our dataset) and Eosinophil versus HC. (B) 2 of 371 genes (0.54%) were common between the DEG from a recently published ACLF neutrophil dataset (GSE142254) and the eosinophil dataset revealed an overlap of 2 of 371 genes (0.54%), which was comparable. (C) 94 genes were common in the comparative analysis of ACLF versus HC (our study) with the published ACLF neutrophil dataset (GSE142254; named as Neutrophil (ACLF vs HC)) and 62 were common between genes between ACLF versus CLD (our dataset) versus Neutrophil (ACLF vs HC).

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