Table 2 Symptoms of CuATSM–associated toxicity, including weight loss, posture abnormalities and activity.

From: CuATSM improves motor function and extends survival but is not tolerated at a high dose in SOD1G93A mice with a C57BL/6 background

Symptom

Vehicle (n = 20)

CuATSM (n = 20)

Weight loss*

0

7

Hunched posture

0

6

Orbital tightening

0

5

Piloerection

0

5

Hypoactive

0

5

  1. *Weight loss was defined as 10% body weight loss since beginning treatment.
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