Table 3 Immunohistochemical evaluation of axonal outgrowth and number of S100 positive cells in the matrix and in the distal nerve segment of rat sciatic nerve defects, bridged by different densities of carbon nanotube yarn in 8 weeks after the transplantation.
From: Carbon-nanotube yarns induce axonal regeneration in peripheral nerve defect
C0 (n = 7) | CN2 (n = 7) | CN5 (n = 7) | CN10 (n = 7) | CN35 (n = 7) | |
|---|---|---|---|---|---|
IR of Neurofilament (% of proximal portion) | |||||
P5/P | 8.9 ± 6.9 | 95.7 ± 12.2*** | 87.6 ± 11.7*** | 56.6 ± 12.0** | 0 ± 0 |
D5/P | 0.2 ± 0.2 | 72.9 ± 15.3*** | 84.9 ± 10.8*** | 19.4 ± 7.9* | 0 ± 0 |
D/P | 0 ± 0 | 62.6 ± 5.4*** | 67.7 ± 9.6*** | 14.9 ± 7.5 | 0 ± 0 |
Number of S100 + cells (% of proximal portion) | |||||
P5/P | 19.7 ± 12.6 | 77.9 ± 7.3** | 63.5 ± 9.8* | 55.3 ± 8.9 | 0 ± 0 |
D5/P | 0 ± 0 | 69.0 ± 17.6** | 57.1 ± 4.3* | 31.7 ± 7.9 | 0 ± 0 |
D/P | 77.3 ± 11.6 | 95.6 ± 20.1 | 73.7 ± 8.0 | 82.3 ± 6.7 | 57.4 ± 10.8 |
