Figure 6

Proliferative capacity of human colonic macrophages. (A) Identification of human colonic Ki67 + macrophages isolated from lamina propria tissue of healthy colon biopsies. (B) Quantification of Ki67 + CD206 + and Ki67 + CD206⁻ macrophage populations in healthy and CD tissue. Error bars show + SD. n = 9 for both CD206⁻ and CD206 + . (C) Immunohistochemical staining of representative healthy and CD colonic cells cells for CD68 (left column) and Ki67 (right column). (D) Proliferation comparison between healthy and CD tissue. Example of gating, and frequencies of CD206⁻ and CD206 + macrophages in G2 in healthy and CD tissue.