Figure 3 | Scientific Reports

Figure 3

From: TYROBP, TLR4 and ITGAM regulated macrophages polarization and immune checkpoints expression in osteosarcoma

Figure 3

Validation of the prognostic gene signature for osteosarcoma using GSE21257 cohort. (A) Classification of patients into different risk groups based on the median risk score. (B) Distribution of patients’ survival time and status. (C) Heatmap of expression profiles of included risk score related genes. (D) Kaplan–Meier survival curves between low- and high-risk groups in the GSE21257 cohort. (E) ROC curves of the risk score diagnostic ability. GSEA in the Hallmarks (F) and KEGG (G) gene set between group high (n = 42) and low (n = 42) of the risk score in the TCGA cohort.

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