Table 3 Pattern of association between gene pathways and increased concentrations of multiple particulate matter pollutants at multiple lag times (bold-upregulated, italics-downregulated).

Establishment_of_protein_localization_to_endoplasmic_reticulum

21–27

7–13

0–6

7–13

14–20

Ribosomal_subunit

21–27

7–13

0–6

7–13

14–20

Structural_constituent_of_ribosome

21–27

7–13

0–6

7–13

14–20

Specific_granule_lumen

21–27

0–6

0–6

0–6

Cotranslational_protein_targeting_to_membrane

21–27

7–13

0–6

14–20

Cytosolic_large_ribosomal_subunit

21–27

7–13

0–6

7–13

Cytosolic_ribosome

21–27

7–13

0–6

14–20

Ferric_iron_binding

0–6

21–27

21–27

0–6

Ferrous_iron_binding

0–6

21–27

21–27

0–6

Large_ribosomal_subunit

21–27

7–13

0–6

14–20

Nuclear_transcribed_mrna_catabolic_process_nonsense_mediated_decay

21–27

7–13

0–6

14–20

Protein_localization_to_endoplasmic_reticulum

21–27

7–13

0–6

14–20

Protoporphyrinogen_Ix_biosynthetic_process

0–6

21–27

0–6

0–6

Protoporphyrinogen_Ix_metabolic_process

0–6

21–27

0–6

0–6

Ribosome

21–27

7–13

0–6

14–20

Translational_initiation

21–27

7–13

0–6

14–20

Catalytic_step_2_spliceosome

0–6

21–27

14–20

Mitochondrial_translation

0–6

21–27

7–13

U2_type_catalytic_step_2_spliceosome

0–6

21–27

7–13

U2_type_spliceosomal_complex

0–6

21–27

7–13

Nuclear_transcribed_mrna_catabolic_process

21–27

0–6

14–20

Translation_preinitiation_complex

14–20

0–6

7–13

Specific_granule

0–6

0–6

0–6

Small_ribosomal_subunit

21–27

7–13

14–20

Cytoplasmic_translation

21–27

14–20

14–20

Cytosolic_small_ribosomal_subunit

21–27

7–13

14–20

Protein_targeting_to_membrane

21–27

7–13

14–20

Viral_gene_expression

21–27

7–13

14–20

Cytoplasmic_side_of_rough_endoplasmic_reticulum_membrane

7–13

7–13

General_transcription_initiation_factor_activity

21–27

21–27

Mitochondrial_gene_expression

21–27

7–13

Myeloid_leukocyte_mediated_immunity

0–6

7–13

Positive_regulation_of_double_strand_break_repair_via_homologous_recombination

21–27

21–27

Secretory_granule_membrane

0–6

7–13

Specific_granule_membrane

0–6

0–6

Superoxide_anion_generation

0–6

7–13

Tertiary_granule

0–6

7–13

Autolysosome

21–27

21–27

Oxidoreductase_activity_oxidizing_metal_ions

21–27

21–27

Oxidoreductase_activity_oxidizing_metal_ions_oxygen_as_acceptor

21–27

21–27

Regulation_of_ryanodine_sensitive_calcium_release_channel_activity

21–27

21–27

T_cell_receptor_binding

14–20

14–20

Mda_5_signaling_pathway

0–6

0–6

Polysomal_ribosome

21–27

14–20

Polysome

21–27

21–27

Cajal_body

0–6

14–20

Lewy_body

0–6

0–6

Porphyrin_containing_compound_metabolic_process

0–6

0–6

Regulation_of_mitochondrial_electron_transport_nadh_to_ubiquinone

0–6

0–6

Spectrin_associated_cytoskeleton

0–6

0–6

Hemoglobin_metabolic_process

7–13

0–6

Purine_deoxyribonucleotide_binding

0–6

0–6