Table 3 Comparation of ondansetron-induced gene expression profiles with three AKI gene expression profiles.

From: Effect of ondansetron on reducing ICU mortality in patients with acute kidney injury

Biosets

Bioset Name

Genes

Overlap p value

Common Genes

Bioset 1 (Ondansetron)

Intestine of rats + ONDANSETRON at 84 mg-kg in water by oral gavage 0.25d _vs_ vehicle (GEO ID: GSE59927)

1815

Bioset 2(AKI)

Kidney from transplant patient with toxic drug effects and UTI _vs_ normal kidney (GEO ID: GSE362)

3289

4.0E−08

269

Bioset 3 (AKI)

Kidney from transplant patient with toxic drug effects _vs_ normal kidney (GEO ID: GSE409)

4417

9.8E−07

345

Bioset 4(AKI)

Kidney from transplant patient with toxic drug effects, UTI, and ARII_vs_ normal kidney (GEO ID: GSE410)

4695

4.9E−06

345

  1. UTI: urinary tract infection, ARII: acute rejection type II.