Table 1 Genotypes of progeny from Atp6v0c+/− mating.

From: Vacuolar-type proton ATPase is required for maintenance of apicobasal polarity of embryonic visceral endoderm

Age

Atp6v0c genotype

 

+/+

+/−

−/−

Resorptions

Chi-Square Test

E 3.5

9 (20%)

23 (52%)

12 (27%)

0 (0%)

p = 0.78

E 4.5

16 (26%)

30 (49%)

15 (25%)

0 (0%)

p = 0.98

E 5.0

21 (28%)

40 (53%)

7 (9%)

7 (9%)

p = 0.02

E 5.5

109 (25%)

234 (54%)

70 (16%)

40 (9%)

p = 0.0006

3–4 wks

47 (29%)

114 (71%)

0 (0%)

0 (0%)

p = 9.7 × 10–13

  1. Timed mating was set up, and the isolated embryos or tails were used to obtain the genomic DNA. We were unable to genotype the resorptions.
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