Figure 2
From: Potential roles of 1,5-anhydro-d-fructose in modulating gut microbiome in mice
Comprehensive map of the metabolic pathways upregulated or downregulated by dietary supplementation with 1,5-AF. The metagenomic reads of the gut microbiota in mice treated with or without 1,5-AF (n = 8 in each group) were mapped against a functional reference database, and gene abundances were determined as reads per kilobase of exon per million mapped sequence reads (RPKM). The differences in RPKM values between the 1,5-AF-treated mice and the control mice were analysed using White’s non-parametric t-test with FDR adjustment for multiple comparison. Significantly more or less abundant genes in the gut microbiota of the 1,5-AF-treated mice are shown with red or blue lines, respectively. The metabolic map was created using the Kyoto Encyclopedia of Genes and Genomes (KEGG) mapper28 with the copyright permission.
