Figure 5
Indicator species analysis of AD microbiome within four metagenomics groups. (A) Individual group effects of the indicator species associated with energy production, (B) combined group effects of the indicator species associated with energy production. Indicator values (IndVal) plotted next to the name of taxa range from zero to one, with larger values denoting greater specificity. Indicator values (IndVal) are shown next to the taxonomic information for the indicator taxa as indicated by Indicator. Size of symbol ((circle size) is proportional to the mean relative abundance in that group of AD and p-values (circle color) were plotted. Circles colored in grey indicate insignificant taxa. Higher indicator values (IVs) suggested better performances in the microbial signature of the assigned taxa. The R package, Indicspecies (https://cran.r-project.org/web/packages/indicspecies/index.html) was used to analyze the data, and ggplot2 (https://cran.r-project.org/web/packages/ggplot2/index.html) was used to draw these bubble groups.
