Figure 5
CFU comparison between untreated and treated groups. Log10 CFU counts in lungs and spleen of untreated and INH + RIF treated latent tuberculosis and latent tuberculosis with diabetes group (A) Lungs (B) Spleen. The data were represented as Mean ± SE of 5 animals in each group and the statistical significance was determined by Mann–Whitney test. *p ≤ 0.05. Group-Ia: latent tuberculosis untreated, Group-Ib: latent tuberculosis treated with INH + RIF, Group-IIa: latent tuberculosis with diabetes untreated, Group-IIb: latent tuberculosis with diabetes treated with INH + RIF. Animal model was developed only once but CFU enumeration was done in triplicates from each animal.
