Figure 7

The mechanism of phoP/phoQ(pcDNA3.1-L1-siE6) inhibiting the growth of xenograft tumors in vivo. (A) ELISA analysis of anti-HPV16-L1 antibody in serum after treated with phoP/phoQ. *P < 0.05, vs the control group. (B,C) ELISA anal-ysis of IL-2 and IFN-γ in serum after treated with phoP/phoQ. *P < 0.05, vs the control group. (D–F) Immunohistochemical analysis of HPV-L1/E6/E7 protein expression in Siha xenografts treated with phoP/phoQ (× 400).