Table 1 Clinical characteristics of patients with and without viral respiratory tract infections (VRTIs).
From: Respiratory viral infections in pragmatically selected adults in intensive care units
All (n = 158) | With VRTIs (n = 64) | Without VRTIs (n = 94) | p value | |
|---|---|---|---|---|
Demographic | ||||
Age | 68 (57–77) | 63 (50–75) | 69 (60.25–79) | 0.008 |
Male sex | 87 (55%) | 29 (45.3%) | 58 (61.7%) | 0.268 |
Hospital stay | 16 (10–28) | 16 (10–25.25) | 16 (10–29.75) | 0.980 |
Comorbidity | ||||
Hypertension | 72 (45.6%) | 29 (45.3%) | 43 (45.7%) | 0.974 |
Diabetes mellitus | 47 (29.7%) | 19 (29.7%) | 28 (29.8%) | 0.992 |
Chronic kidney disease | 45 (28.5%) | 19 (29.7%) | 24 (27.7%) | 0.836 |
Heart failure | 37 (23.4%) | 16 (25.0%) | 21 (22.3%) | 0.761 |
Coronary artery disease | 28 (17.7%) | 14 (21.9%) | 14 (14.9%) | 0.348 |
COPD | 25 (15.8%) | 8 (12.5%) | 17 (18.1%) | 0.419 |
Malignancies | 24 (15.2%) | 8 (12.5%) | 16 (17.0%) | 0.503 |
Autoimmune diseases | 11 (7.0%) | 3 (4.5%) | 8 (8.7%) | 0.529 |
Bronchiectasis | 8 (5.0%) | 5 (7.8%) | 3 (3.2%) | 0.279 |
Asthma | 4 (2.5%) | 2 (3.1%) | 2 (2.1%) | 1.000 |
Hepatic cirrhosis | 2 (1.3%) | 0 (0%) | 2 (2.1%) | 0.517 |
Severity and outcomes | ||||
Vasopressor use | 64 (40.5%) | 26 (40.6%) | 38 (40.4%) | 1.000 |
Septic shock | 32 (20.3%) | 15 (23.4%) | 17 (18.1%) | 0.638 |
Mechanical ventilation | 128 (81.0%) | 52 (81.3%) | 76 (80.9%) | 0.984 |
ARDS | 60 (38.0%) | 29 (45.3%) | 31 (33.0%) | 0.297 |
Moderate-to-severe | 46 (29.1%) | 21 (32.8%) | 25 (26.6%) | 0.533 |
APACHE IIa | 21.23 ± 7.66 | 19.98 ± 6.98 | 22.09 ± 8.10 | 0.083 |
SOFA scoreb | 7.25 ± 3.71 | 7.44 ± 3.56 | 7.12 ± 3.81 | 0.590 |
MV days | 4 (2–10) | 4.5 (2–9.25) | 4 (2–12) | 0.892 |
ICU stay | 8 (5–14) | 8 (5–13) | 8 (5–14) | 0.691 |
Hospital stay | 16 (10–28) | 16 (10–25.25) | 16 (10–29.75) | 0.980 |
ICU mortality | 24 (15.2%) | 7 (10.9%) | 17 (18.1%) | 0.289 |
28-day mortality | 23/152 (15.1%) | 8/62 (12.9%) | 15/90 (16.7%) | 0.584 |
