Figure 1
From: Insight into the interaction between the RNA helicase CGH-1 and EDC-3 and its implications
Structural model of CGH-1 RecA2 domain in complex with EDC-3 FDF-FEK. (A) Schematic view of domain architecture of C. elegans CGH-1. RecA1 and RecA2 domain are colored in violet and cyan, respectively. The construct of RecA2 domain employed in this work was also shown. (B) Sequence alignment of CGH-1248–420 and its orthologs. The residues for site-directed mutation in this study were marked with blue boxes. The secondary structures were also indicated in this panel. (C) Schematic view of domain architecture of C. elegans EDC-3. LSm domain, FDF domain, and YjeF-N domain are colored in blue, yellow and brown, respectively. (D) Sequence alignment of Ce EDC-3235–271 and its orthologs. DFDF and FxK are represented by triangles and squares, respectively. The second structures were also shown in this panel. (E) Overall view of this model shown in cartoon. CGH-1 RecA2 domain and EDC-3 FDF are colored in cyan and yellow, respectively.
