Table 4 Tortuosity metrics statistical correlation to the low TAWSS < 0.4 Pa normalized vessel area coverage.

From: Accuracy of vascular tortuosity measures using computational modelling

 

LMCA

LAD

LCx

Complete bifurcation

R2

p-value

R2

p-value

R2

p-value

R2

p-value

Tortuosity index

 − 0.011

0.660

0.026

0.099

0.007

0.276

 − 0.018

0.865

Average absolute-curvature

0.196

 < 0.001***

0.232

 < 0.001***

0.061

0.013*

0.112

0.001***

RMS-curvature

0.113

 < 0.001***

0.164

 < 0.001***

0.010

0.236

0.093

0.002**

Average squared-derivative-curvature

0.086

0.003**

0.160

 < 0.001***

0.007

0.274

0.101

0.001***

  1. Higher R2 indicates better performance, i.e. the predictors account for a larger proportion of the variance observed in TAWSS. Note that R2 has been adjusted for multiple predictors and hence may be negative particularly for underperforming models.
  2. *p ≤ 0.05; **p ≤ 0.01; ***p ≤ 0.001.