Table 1 Characteristics of study participants.
COPD (n = 14) | Healthy controls (n = 12) | p value | |
|---|---|---|---|
Age, years | 65 ± 8 | 65 ± 7 | 0.633 |
Female, n (%) | 7 (50) | 5 (42) | 0.347 |
BMI, kg/m2 | 25 ± 3 | 24 ± 2 | 0.723 |
FFM, % | 39 ± 5 | 37 ± 4 | 0.076 |
Smoking status, n (%) | < 0.001 | ||
Former | 14 (100) | 3 (25) | |
Never | 0 (0) | 9 (75) | |
FEV1, % of predicted | 38 ± 8 | 119 ± 13 | < 0.001 |
FVC, % of predicted | 88 ± 12 | 127 ± 15 | < 0.001 |
FEV1/FVC, % | 35 ± 7 | 76 ± 4 | < 0.001 |
RV, % predicted | 159 ± 40 | 78 ± 14 | < 0.001 |
DLCO, % predicted | 45 ± 11 | 80 ± 13 | < 0.001 |
mMRC dyspnea scale (0–4) | 2.7 ± 0.5 | 1.7 ± 0.5 | < 0.001 |
Voorrips physical activity | 5.6 ± 2.0 | 7.3 ± 2.8 | 0.172 |
1STS, number of repetitions | 24 ± 5 | 31 ± 6 | 0.009 |
1STS, total work, repetitions*kg | 1603 ± 517 | 2011 ± 540 | 0.006 |