Table 3 Adjusted multiple logistic regression results in NHS and AFRICOS, excluding participants with CD4 nadir > 350 cells/µl.

From: Clinical factors and outcomes associated with immune non-response among virally suppressed adults with HIV from Africa and the United States

Characteristic

Adjusted OR (95% CI)

p value

Natural history studya

Age at ART initiation (years)

1.00 (0.99, 1.03)

0.506

Sex

  

Female

0.67 (0.34, 1.33)

0.254

Male

Reference

 

CD4 nadir (cells/µl) (per 100 cells)

0.34 (0.28, 0.41)

< 0.001

History of diabetesc

  

Yes

2.17 (1.11, 4.25)

0.024

No

Reference

 

African Cohort Studyb

Age at ART initiation (years)

1.05 (1.03, 1.07)

< 0.001

Sex

 

< 0.001

Female

0.49 (0.35, 0.71)

 

Male

Reference

 

CD4 nadir (cells/µl) (per 100 cells)

0.46 (0.37, 0.56)

< 0.001

History of diabetesc

  

Yes

0.87 (0.52, 1.46)

0.606

No

Reference

 
  1. a842 participants in NHS with baseline CD4 > 350 cells/µl excluded.
  2. b210 participants in AFRICOS with baseline CD4 > 350 cells/µl excluded.
  3. cDefined as a diagnosis occurring before sustained VS was achieved.
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