Table 2 Summary of mitochondrial morphological features.

From: Differential remodelling of mitochondrial subpopulations and mitochondrial dysfunction are a feature of early stage diabetes

 

SSM

IFM

PNM

Dimensions of mitochondrial tubular projections

Wild type (WT)

 No. of projections

32

20

39

 Length (µm)

0.574 ± 0.415

0.432 ± 0.242

0.488 ± 0.316

 Width (µm)

0.220 ± 0.068

0.253 ± 0.106

0.215 ± 0.075

GENA348

 No. of projections

48

39

46

 Length (µm)

0.847 ± 0.556

0.585 ± 0.391

0.618 ± 0.322

 Width (µm)

0.271 ± 0.073

0.225 ± 0.057

0.232 ± 0.014

Cristae parameters

Wild type (WT)

 No. of cristae

278

301

195

 WO (nm)

34 ± 3

36 ± 3

38 ± 6

 WI (nm)

16 ± 1

16 ± 1

17 ± 3

 S (nm)

28 ± 3

27 ± 4

29 ± 3

GENA348

 No. of cristae

302

310

255

 WO (nm)

34 ± 6

37 ± 3

38 ± 1

 WI (nm)

16 ± 2

17 ± 2

17 ± 1

 S (nm)

23 ± 5

25 ± 2

26 ± 2

  1. N = 3 per group. Data are presented as the mean ± s.d.