Figure 2

Epithelial–mesenchymal transition (EMT) is the top hallmark gene set in both tumor and non-tumor cell genes determined by GSEA. (A, B) 12/72 tumor genes and 11/55 non-tumor genes are involved in epithelial mesenchymal transition (EMT) pathway, identified by http://www.gsea-msigdb.org/gsea/msigdb. Top hallmark gene sets were presented in bar graphs. (C, D) Gene expression in heatmap: 12/72 tumor genes and 11/55 non-tumor genes. Gene set enrichment analysis (GSEA) was computed to identify the overlaps with hallmark gene sets in Molecular Signatures Database (MSigDB) Collections. with FDR q-value less than 0.05.