Figure 4
From: Identification of an allatostatin C signaling system in mollusc Aplysia
source of the sequences. (C) Somatostatin 14 and somatostatin 28 in mammals. Note that there are six amino acids between the two cysteines of allatostatin C in invertebrates, vs. ten amino acids between the two cysteines of somatostatins in mammals. –S–S– disulfide bridge.
Comparison of AstCs from invertebrates, and with somatostatins in vertebrates. Comparison of selected AstC peptides from invertebrates using BioEdit (ClustalW Multiple alignment—Graphic View) (A) and a frequency plot for these sequences using Weblogo v2.8.2 (http://weblogo.berkeley.edu/logo.cgi) (B). pQ indicates pyro-glutamic acid. At the right part of panel A, numbers denote the number of amino acids in a peptide, and # indicates that the sequence has been verified or studied before. See Supplementary Table 3 for the
