Figure 11 | Scientific Reports

Figure 11

From: A comprehensive physiologically based pharmacokinetic (PBPK) model for nicotine in humans from using nicotine-containing products with different routes of exposure

Figure 11

Simulation of the intravenous administration of nicotine in human26. Subjects (N = 22) were administered nicotine at a rate of 2 µg/kg/min for 30 min; dotted line represents data from study and solid lines represent simulation results. Red lines and dots correspond to arterial blood and blue lines and dots to venous blood.

Back to article page