Figure 16 | Scientific Reports

Figure 16

From: A comprehensive physiologically based pharmacokinetic (PBPK) model for nicotine in humans from using nicotine-containing products with different routes of exposure

Figure 16

Simulation of the nicotine venous plasma time-course in 16 ENDS-naïve cigarette smokers after two uses (1 h interval) of an ENDS device reported32. The nicotine content of the e-liquids was reported as 8, 18, and 36 mg/mL. Subjects were asked to take 10 puffs with 30 s puff intervals. Error bars represent one standard deviation.

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