Figure 2
From: Prognostic implications of N6-methyladenosine RNA regulators in breast cancer
The expression of m6A regulator genes and clustering of samples. (A) Differential heatmap of 13 m6A regulator genes in breast cancer. Red indicates upregulation, and green indicates downregulation. Blue represents normal tissue and red represents breast cancer tissue. *P < 0.05, **P < 0.01, ***P < 0.001. (B) A violin plot of differential expression of 13 m6A regulator genes in breast cancer. Blue represents normal tissue and red represents breast cancer tissue. (C) Correlation analysis of m6A regulator genes. Red represents positive correlation, blue represents negative correlation. (D–F) Identification of consensus clusters by 13 m6A regulator genes. (D) The consensus cumulative distribution function (CDF) of the consensus matrix for each K (colored). (E) The Delta area diagram shows the relative change of area under the CDF curve. (F) The consensus matrix displays the cluster membership marked by colored rectangles, enabling users to calculate the number of cluster members in their consensus context. (G) Reliability analysis of tumour consensus clusters. Red represents cluster 1 and blue represents cluster 2. (H) Survival analysis of two tumour clusters. Red represents cluster 1 and blue represents cluster 2.
