Figure 2
From: Spontaneous and TMS-related EEG changes as new biomarkers to measure anti-epileptic drug effects
TRSP modulated by Lamotrigine (experiment 1). Grand averages of the time–frequency representation (TFR averaged over ROI channels) of TRSP recorded before (pre) and after (post) the intake of Lamotrigine are shown on the left panel. The blue boxes correspond to the time window when comparison between pre and post conditions showed significant drug effects. Topographical distributions of drug-related effects on delta (p = 0.01, 30–160 ms), theta (p = 0.006, 120–390 ms) and alpha band power (p = 0.02, 350–510 ms) are reported for pre and post drug conditions on the right panel. Significant electrodes within the bilateral 27 electrode ROIs are represented with asterisks in the t-statistic map.
