Table 9 Egg cholesterol content (Mean ± standard deviation) in transgenic (n = 2 for ACACA transgenic group and n = 2 for SREBP1 transgenic group) and control broiler birds (n = 2) at 52 weeks of age during 1st generation.

From: Silencing acetyl-CoA carboxylase A and sterol regulatory element-binding protein 1 genes through RNAi reduce serum and egg cholesterol in chicken

 

Egg wt (g)

Total cholesterol (mg/100 g of egg)

LDL (mg/100 g of egg)

Control group

60.0 ± 1.8

509.3 ± 27.1

432.6 ± 11.1

ACACA transgenic group

55.0 ± 1.3

436.1 ± 33.0

387.5 ± 20.9

P

0.2263

0.0577

0.0574

Percent change in ACACA transgenic group (%)

− 8.3

− 14.3

− 10.4

SREBP1 transgenic group

62.07 ± 1.6

441.7 ± 33.4

373.2 ± 46.5

P

0.4020

0.0579

0.0522

Percent change in SREBP1 transgenic group (%)

3.4

13.2

13.7

  1. The total cholesterol and LDL content in eggs were measured in knock down and control groups.
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