Table 1 Characteristics of included studies.
Authors | Year | Country | Acronyme | Period | Patients, n | Population | Intervention | Control | Primary outcome |
|---|---|---|---|---|---|---|---|---|---|
Richards et al | 2020 | United Kingdom | PREVENTT | 01.2014–09.2018 | 135 | Major open abdominal surgery with anaemia | IV 1000 mg iron 10-42d before surgery | Placebo | Blood transfusion/death from randomization to POD30 |
Froessler et al | 2016 | Australia | – | 08.2011–11.2014 | 72 | Major open abdominal surgery with iron-deficiency anaemia | IV 15 mg/kg ferric carboxymaltose 4-21d before surgery + 0.5 mg/ml blood loos if ≥ 100 ml before POD2 | Usual care | Blood transfusion |
Lidder et al | 2007 | United Kingdom | – | – | 45 | Colorectal cancer surgery | Oral ferrous sulphate 200 mg 3×/day for 2 weeks before surgery | Usual care | Hemoglobin concentration |
Edwards et al | 2009 | United Kingdom | – | 05.2006–08.2008 | 60 | Colorectal cancer surgery | IV 600 mg iron sucrose 14d before surgery | Placebo | Hemoglobin concentration at admission |