Table 1 Characteristics of included studies.

From: Pre-operative iron increases haemoglobin concentration before abdominal surgery: a systematic review and meta-analysis of randomized controlled trials

Authors

Year

Country

Acronyme

Period

Patients, n

Population

Intervention

Control

Primary outcome

Richards et al

2020

United Kingdom

PREVENTT

01.2014–09.2018

135

Major open abdominal surgery with anaemia

IV 1000 mg iron 10-42d before surgery

Placebo

Blood transfusion/death from randomization to POD30

Froessler et al

2016

Australia

08.2011–11.2014

72

Major open abdominal surgery with iron-deficiency anaemia

IV 15 mg/kg ferric carboxymaltose 4-21d before surgery + 0.5 mg/ml blood loos if ≥ 100 ml before POD2

Usual care

Blood transfusion

Lidder et al

2007

United Kingdom

45

Colorectal cancer surgery

Oral ferrous sulphate 200 mg 3×/day for 2 weeks before surgery

Usual care

Hemoglobin concentration

Edwards et al

2009

United Kingdom

05.2006–08.2008

60

Colorectal cancer surgery

IV 600 mg iron sucrose 14d before surgery

Placebo

Hemoglobin concentration at admission