Table 1 Structures of GLUT3 inhibitors.

From: GLUT3 inhibitor discovery through in silico ligand screening and in vivo validation in eukaryotic expression systems

  1. For each GLUT3 inhibitor, the ChemNavigator structural ID, SMILES code, and IC50 values for GLUT3 inhibition are indicated. Corresponding dose–response curves are in Fig. 2B–G. G3iA, G3iB, and G3iD are inhibitors resulted from TBVS of the outward-facing GLUT3 conformation; G3iC, G3iE, and G3iF are inhibitors produced by TBVS of the inward-facing GLUT3 conformation.
Back to article page