Figure 2 | Scientific Reports

Figure 2

From: Sodium–calcium exchanger isoform-3 targeted Withania somnifera (L.) Dunal therapeutic intervention ameliorates cognition in the 5xFAD mouse model of Alzheimer’s disease

Figure 2

Y-maze spontaneous alternation task for spatial working memory test of 4-month-old 5xFAD mice after 45 consecutive days (P30-75) treatment with W. somnifera. Schematic diagram of Y-maze task (A), and data that compare the percentage alternation behavior (B) and their average number of arm entries (C). The data represent the mean ± SEM. Data were from 12 different mice in each group (n = 12) using one-way ANOVA followed by Tukey’s multiple comparisons test. Significance is indicated by *p < 0.05; **p < 0.01 versus vehicle; by †p < 0.05 between W. somnifera treated groups; by ‡p < 0.05 between W. somnifera and Res treated groups. Vehicle control group, LDT low dose treatment, HDT high dose treatment, Res Resveratrol.

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