Table 2 In vitro anticancer activity of hydroxyxanthone derivatives.
From: Synthesis and in vitro assay of hydroxyxanthones as antioxidant and anticancer agents
Compound | IC50 (µM) | |||
|---|---|---|---|---|
Vero39 | MCF-7 | WiDr | HeLa | |
3a | 3395 ± 435 | 184 ± 15 | 254 ± 15 | 277 ± 9 |
3b | 308 ± 35 | 450 ± 17 | 355 ± 24 | 322 ± 4 |
3c | 224 ± 14 | 419 ± 27 | 209 ± 4 | 241 ± 13 |
Doxorubicin | 150 ± 3 | 71 ± 6 | 3 ± 0.2 | – |
Cisplatin | – | – | – | 142 ± 52 |
