Table 4 Comparison of in vitro anticancer activity of hydroxyxanthone derivatives against WiDr cancer cell line.

From: Synthesis and in vitro assay of hydroxyxanthones as antioxidant and anticancer agents

Compound

IC50 (µM)

SI

Reference

WiDr

1,3,8-trihydroxyxanthone (3a)

254 ± 15

13.39

This work

1,6-dihydroxyxanthone (3b)

355 ± 24

0.870

1,5,6-trihydroxyxanthone (3c)

209 ± 4

1.072

1,3-dihydroxyxanthone

836 ± 109

2.230

33

3,4-dihydroxyxanthone

1255 ± 105

1.160

3,6-dihydroxyxanthone

786 ± 146

1.630

1,3,6-trihydroxyxanthone

384 ± 93

1.540

3,4,6-trihydroxyxanthone

38 ± 11

66.39

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