Figure 2

Effects of endurance exercise training and PGC-1α overexpression on lactate production volume. Blood lactate concentrations of CON and EX or WT and PGC-1α OE at each exercise intensity during incremental exercise test (A, D). The lactate production volume during a 2-min exercise calculated using Eq. (2) utilizing the experimental data (B, E). Simulated lactate production volume in response to 4 mM blood lactate concentration in each group (C, F). Data are expressed as mean ± SEM. n = 7 in the CON and EX groups. n = 5 in the WT and PGC-1α OE groups. *P < 0.05, **P < 0.01, ***P < 0.001.