Table 2 The association of cognitive function, corneal nerve fiber measures, cingulate gyrus volume with schizophrenia after adjustment for cofounders.
From: Abnormal corneal nerve morphology and brain volume in patients with schizophrenia
Adjusted mean difference | 95% confidence interval | P value | |
|---|---|---|---|
CNFD (fibers/mm2) (min.–max: 10.4–49.1) | |||
Schizophrenia | − 5.2 | − 9.4, − 1.0 | < 0.05 |
Smoking cigarette | − 6.5 | − 11.2, − 1.8 | < 0.01 |
BMI (kg/m2) | − 0.4 | − 0.6, − 0.1 | 0.01 |
VPT (V) | − 0.6 | − 1.0, − 0.1 | 0.01 |
CNBD (branches/mm2) (min.–max: 7.6–142.2) | |||
Schizophrenia | − 41.4 | − 62.0, − 20.8 | < 0.0001 |
BMI (kg/m2) | − 0.3 | − 1.3, 0.8 | 0.63 |
Sleep (h) | − 3.0 | − 6.4, 0.4 | 0.08 |
CNFL (mm/mm2) (min.–max: 5.9–32.9) | |||
Schizophrenia | − 7.1 | − 10.6, − 3.6 | < 0.0001 |
BMI (kg/m2) | − 0.1 | − 0.1, 0.3 | 0.18 |
Sleep (h) | − 0.3 | − 0.2, 0.9 | 0.23 |
CNBD:CNFD ratio (min.–max: 0.4–4.1) | |||
Schizophrenia | − 0.3 | − 0.9, 0.3 | 0.33 |
Cingulate gyrus (ICV %) | 4.6 | 1.2, 8.1 | 0.01 |
Hippocampus (ICV %) | 3.1 | − 2.5, 8.6 | 0.26 |
ESC feet (µS) | 0.02 | 0.01, 0.03 | < 0.01 |
Cingulate gyrus (ICV %) (min.–max: 0.70–1.04) | |||
Schizophrenia | − 0.07 | − 0.13, − 0.01 | < 0.05 |
