Table 1 Descriptive statistics for individuals with calculated femininity score.
Overall | Women | Men | p-value | |
|---|---|---|---|---|
N = 315,937 | n = 166,706 (53%) | n = 149,231 (47%) | ||
Age, years [mean (SD)] | 56.6 (8.0) | 56.4 (7.9) | 56.9 (8.0) | < 0.001 |
Height, cm [mean (SD)] | 169.1 (9.2) | 162.9 (6.2) | 176.1 (6.7) | < 0.001 |
Waist-hip ratio [mean (SD)] | 0.87 (0.09) | 0.82 (0.07) | 0.93 (0.06) | < 0.001 |
BMI, kg/m2 [mean (SD)] | 27.4 (4.7) | 27.0 (5.1) | 27.8 (4.2) | < 0.001 |
SBP, mmHg [mean (SD)] | 137.9 (18.5) | 135.1 (19.0) | 141.1 (17.3) | < 0.001 |
DBP, mmHg [mean (SD)] | 82.3 (10.1) | 80.6 (9.9) | 84.1 (10.0) | < 0.001 |
Prevalent hypertension (%) | 292,512 (92.6) | 156,326 (93.8) | 136,186 (91.3) | < 0.001 |
Townsend deprivation index [mean (SD)] | − 1.56 (2.94) | − 1.58 (2.89) | − 1.54 (2.98) | 0.002 |
Current smoking (%) | 31,228 (9.9) | 14,284 (8.6) | 16,944 (11.4) | < 0.001 |
Biomarker measurements | ||||
Triglycerides, mmol/L [mean (SD)] | 1.75 (1.03) | 1.55 (0.86) | 1.98 (1.15) | < 0.001 |
Total cholesterol, mmol/L [mean (SD)] | 5.71 (1.14) | 5.89 (1.12) | 5.51 (1.12) | < 0.001 |
HDL, mmol/L [mean (SD)] | 1.45 (0.38) | 1.60 (0.38) | 1.29 (0.31) | < 0.001 |
LDL, mmol/L [mean (SD)] | 3.57 (0.87) | 3.64 (0.87) | 3.49 (0.86) | < 0.001 |
HbA1c, mmol/mol [mean (SD)] | 35.9 (6.4) | 35.6 (5.7) | 36.2 (7.1) | < 0.001 |
CV outcomes from hospital records | ||||
MI—incident (%) | 3292 (1.0) | 814 (0.5) | 2478 (1.7) | < 0.001 |
Any angina—prevalent (%) | 7289 (2.3) | 2342 (1.4) | 4947 (3.3) | < 0.001 |
Any angina—incident (%) | 9105 (2.9) | 3067 (1.8) | 6038 (4.0) | < 0.001 |
Angina before incident MI (% of MI cases) | 564 (17.1) | 129 (15.8) | 435 (17.6) | 0.286 |
Femininity score component variables | ||||
Education (%) | ||||
NVQ/HND/HNC/equiv | 40,334 (12.8) | 15,848 (9.5) | 24,486 (16.4) | < 0.001 |
College or University deg | 106,733 (33.8) | 54,204 (32.5) | 52,529 (35.2) | |
None of the above | 49,942 (15.8) | 26,257 (15.8) | 23,685 (15.9) | |
A levels/AS levels/equiv | 37,127 (11.8) | 20,985 (12.6) | 16,142 (10.8) | |
CSE/equiv | 11,103 (3.5) | 6321 (3.8) | 4782 (3.2) | |
Other | 28,840 (9.1) | 16,705 (10.0) | 12,135 (8.1) | |
O levels/GCSEs/equiv | 41,858 (13.2) | 26,386 (15.8) | 15,472 (10.4) | |
Employment (%) | ||||
Unemployed | 4155 (1.3) | 1300 (0.8) | 2855 (1.9) | < 0.001 |
Unable to work due to sickness/disability | 9122 (2.9) | 3892 (2.3) | 5230 (3.5) | |
Paid employment/self-employed | 186,282 (59.0) | 94,075 (56.4) | 92,207 (61.8) | |
None of the above | 106,530 (33.7) | 58,844 (35.3) | 47,686 (32.0) | |
Full- or part-time student | 624 (0.2) | 431 (0.3) | 193 (0.1) | |
Unpaid or volunteer work | 1344 (0.4) | 968 (0.6) | 376 (0.3) | |
Taking care of home and family | 7880 (2.5) | 7196 (4.3) | 684 (0.5) | |
Depression (%) | ||||
Not at all | 246,012 (77.9) | 125,010 (75.0) | 121,002 (81.1) | < 0.001 |
Several days | 56,602 (17.9) | 33,795 (20.3) | 22,807 (15.3) | |
More than half the days | 7964 (2.5) | 4727 (2.8) | 3237 (2.2) | |
Nearly every day | 5359 (1.7) | 3174 (1.9) | 2185 (1.5) | |
Risk-taking (%) | ||||
Yes | 85,416 (27.0) | 33,244 (19.9) | 52,172 (35.0) | < 0.001 |
No | 230,521 (73.0) | 133,462 (80.1) | 97,059 (65.0) | |
Neuroticism score [mean (SD)] | 4.06 (3.24) | 4.52 (3.23) | 3.55 (3.18) | < 0.001 |
Birth year, calendar year [mean (SD)] | 1951.45 (7.96) | 1951.69 (7.88) | 1951.17 (8.04) | < 0.001 |
Vitamin supplement use (%) | ||||
No | 216,287 (68.5) | 107,165 (64.3) | 109,122 (73.1) | < 0.001 |
Yes | 98,963 (31.3) | 59,307 (35.6) | 39,656 (26.6) | |
Missing | 685 (0.2) | 233 (0.1) | 452 (0.3) | |
FS standardized [mean (SD)] | 0.00 (1.00) | 0.26 (1.02) | − 0.29 (0.89) | < 0.001 |
