Figure 4 | Scientific Reports

Figure 4

From: Identification and selection of healthy spermatozoa in heterozygous carriers of the Phe508del-variant of the CFTR-gene in assisted reproduction

Figure 4The alternative text for this image may have been generated using AI.

Immunofluorescent staining of the CFTR membrane channel in three heterozygous carriers of the Phe508del-pathogenic variant of the CFTR-gene and three healthy controls demonstrated by similar percentages of spermatozoa with the CFTR protein in the membrane, both in seminal sperm (A) and in spermatozoa after swim-up or density gradient centrifugation (B). Representative images of spermatozoa stained with the fluorescent anti-CFTR antibody and with the Hoechst 33342-dye (C).

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