Figure 3

Adipogenic gene expression profile of SVF cells obtained from healthy controls (HC) or OI patients at days 7 and 21 in culture. (A) Fold-change of gene expression of treated versus non-treated cells at day 7 of culture. (B) Fold-change of gene expression of treated versus non-treated cells at day 21 of culture. (C) Representative images of oil red staining of treated and non-treated HC and OI samples. HC, n = 2; OI, n = 9; OI-COL1A1, n = 1; OI-COL1A2, n = 6; OI-WNT1, n = 1. Unpaired t-test of genetic fold change of HC versus OI patients showed similar expression for all genes tested.