Figure 4 | Scientific Reports

Figure 4

From: Characterization and functional analysis of the adipose tissue-derived stromal vascular fraction of pediatric patients with osteogenesis imperfecta

Figure 4

Chondrogenic gene expression profile of SVF Cells obtained from healthy Controls (HC) or OI patients at Days 7 and 21 in culture. (A) Fold-change of gene expression of treated versus non-treated cells at day 7 of culture. (B) Fold-change of gene expression of treated versus non-treated cells at day 21 of culture. (C) Representative images of alcian blue staining of treated and non-treated HC and OI samples. HC, n = 2; OI, n = 9; OI-COL1A1, n = 1; OI-COL1A2, n = 6; OI-WNT1, n = 1. Unpaired t-test of genetic fold-change of HC versus all OI patients showed similar expression for all genes tested.

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