Table 1 Basic, clinicopathologic and ultrasound characteristics of treated head and neck SCC patients with recurrent LN.
Characteristics | Non-recurrent LN (N = 41) | Recurrent LN (N = 219) | p value |
|---|---|---|---|
Age (years) | |||
≧50 | 29 (70.73%) | 173 (79%) | 0.31 |
< 50 | 12 (29.27%) | 46 (21%) | |
Gender | |||
Male | 38 (92.68%) | 198 (90.41%) | 0.78* |
Female | 3 (7.32%) | 21 (9.59%) | |
Primary index tumor | |||
Oral cancer | 15 (36.59%) | 121 (55.25%) | 0.02* |
p16- (< 70%) Oropharyngeal cancer | 12 (29.27%) | 44 (20.09%) | |
p16 + (≧70%) Oropharyngeal cancer | 2 (4.88%) | 1 (0.46%) | |
Hypopharyngeal, Laryngeal cancer | 10 (24.39%) | 31 (14.16%) | |
Others | 2 (4.88%) | 22 (10.05%) | |
Previous neck management | |||
Neck dissection only | 9 (21.95%) | 64 (29.22%) | 0.20 |
Radiation only | 22 (53.66%) | 47 (21.46%) | |
Neck dissection and Radiation | 10 (24.39%) | 103 (47.03%) | |
No treatment | 0 | 5 (2.28%) | |
Neck recurrence duration | |||
Acute (≦6 months) | 16 (39.02%) | 66 (30.14%) | 0.28 |
Non-Acute (> 6 months) | 25 (60.98%) | 153 (69.86%) | |
Target LN pathological fibrosis | |||
Fibrotic changes+ | 17 (41.46%) | 55 (25.11%) | 0.04 |
Fibrotic changes− | 24 (58.54%) | 164 (74.89%) | |
Target LN pathological necrosis | |||
Necrosis+ | 8 (19.51%) | 34 (15.53%) | 0.64 |
Necrosis− | 33 (80.49%) | 185 (84.47%) | |
Target LN radiological necrosis | |||
Total necrosis | 2 (4.88%) | 26 (11.87%) | 0.29* |
Partial necrosis | 9 (21.95%) | 59 (26.94%) | |
No necrosis | 30 (73.17%) | 134 (61.19%) | |
Targeted LN level in neck | |||
Upper (I/II/Va) | 25 (60.98%) | 150 (68.49%) | 0.37 |
Lower (III/IV/Vb) | 16 (39.02%) | 69 (31.51%) | |
LN width size | |||
≧1.5 cm | 21 (51.23%) | 179 (81.74%) | < 0.001 |
< 1.5 cm | 20 (48.78%) | 40 (18.26%) | |
Ultrasound characteristic | |||
Ill-defined | 21 (51.22%) | 83 (37.90%) | 0.12 |
Heterogenous | 20 (48.78%) | 89 (40.64%) | 0.39 |
CNB tissue diagnosis | |||
Positive | 0 | 185 (84.47%) | < 0.001 |
Negative | 41 (100%) | 34 (15.53%) | |
