Figure 2

Phylogenetic relationships based on the P1, P2, and P3 coding sequences of all E9 strains, all EV-B prototype strains available in the GenBank database, the five Yunnan isolates, and three EV-B strains (CV-B5/P727/2013/China, CVB4-B4M063015 and E11-1000/ISR/1999), as analyzed by nucleotide sequence alignment with the neighbor joining algorithms implemented in the MEGA 6.06 program. Numbers at nodes indicate bootstrap support for that node (percentage of 1000 bootstrap replicates). The scale bars represent the genetic distance. Only high bootstrap values (> 75%) are shown. Filled triangle: strains isolated in this investigation. Filled circle: E9 strains.