Table 3 Multivariate analysis QOL scores for LRC, DMFS, and OS.

From: Quality of life score as a prognosticator for pharyngeal cancer patients treated with radiotherapy

Variable	LRC				DMFS				OS
Variable	HR	95% CI		p value	HR	95% CI		p value	HR	95% CI		p value
Before treatment
Global QOL	0.890847	0.7282	1.0898	0.2611	0.861	0.751	0.989	0.034	0.864	0.744	1.002	0.054
Physical functioning	0.823	0.646	1.049	0.116	0.906	0.736	1.115	1.115	0.897	0.714	1.128	0.352
Role functioning	0.875	0.750	1.021	0.091	0.936	0.831	1.053	0.272	0.908	0.798	1.032	0.139
Emotional functioning	0.804	0.675	0.956	0.014	0.900	0.792	1.023	0.107	0.874	0.765	0.998	0.047
Cognitive functioning	0.941	0.737	1.201	0.625	0.932	0.792	1.097	0.399	0.918	0.775	1.086	0.318
Social functioning	0.861	0.727	1.020	0.084	0.892	0.788	1.011	0.074	0.881	0.772	1.005	0.059
Fatigue	1.143	0.915	1.429	0.238	1.126	0.976	1.298	0.103	1.159	0.994	1.350	0.060
Nausea/vomiting	0.844	0.438	1.628	0.613	1.139	0.849	1.529	0.387	1.082	0.786	1.490	0.628
Pain	1.115	0.934	1.332	0.229	1.115	0.982	1.267	0.093	1.138	0.992	1.306	0.065
Dyspnea	1.168	0.946	1.442	0.148	0.999	0.835	1.194	0.989	0.983	0.817	1.184	0.858
Insomnia	1.110	0.946	1.303	0.201	1.037	0.921	1.167	0.550	1.017	0.892	1.160	0.799
Appetite loss	1.070	0.911	1.258	0.409	1.108	0.996	1.232	0.060	1.156	1.029	1.299	0.015
Constipation	1.032	0.805	1.322	0.806	1.132	0.976	1.312	0.101	1.117	0.950	1.313	0.180
Diarrhea	0.914	0.658	1.270	0.591	1.096	0.918	1.309	0.313	1.138	0.944	1.373	0.174
1 month after treatment
Global QOL	1.016	0.859	1.201	0.857	0.899	0.799	1.011	0.076	0.930	0.824	1.049	0.237
Physical functioning	0.956	0.821	1.114	0.566	0.935	0.843	1.038	0.207	0.906	0.814	1.009	0.071
Role functioning	0.983	0.856	1.127	0.802	0.968	0.882	1.063	0.499	0.929	0.840	1.027	0.148
Emotional functioning	0.969	0.856	1.096	0.611	0.943	0.866	1.027	0.179	0.961	0.881	1.049	0.378
Cognitive functioning	0.968	0.856	1.094	0.603	0.931	0.856	1.013	0.099	0.957	0.877	1.044	0.320
Social functioning	0.990	0.868	1.128	0.875	0.956	0.873	1.047	0.333	0.967	0.883	1.059	0.468
Fatigue	0.966	0.793	1.177	0.734	0.966	0.843	1.107	0.618	0.982	0.850	1.134	0.804
Nausea/vomiting	1.070	0.772	1.483	0.686	1.032	0.805	1.324	0.803	1.073	0.827	1.391	0.597
Pain	1.044	0.859	1.269	0.668	0.925	0.789	1.084	0.336	0.953	0.808	1.123	0.563
Dyspnea	0.980	0.793	1.209	0.847	0.982	0.854	1.129	0.800	0.969	0.832	1.128	0.685
Insomnia	0.958	0.817	1.124	0.597	0.992	0.891	1.105	0.880	0.989	0.881	1.111	0.857
Appetite loss	0.994	0.868	1.137	0.926	0.989	0.901	1.087	0.824	1.004	0.908	1.110	0.937
Constipation	0.859	0.681	1.084	0.201	0.964	0.828	1.123	0.640	0.908	0.764	1.080	0.277
Diarrhea	1.324	1.079	1.626	0.007	1.304	1.121	1.516	0.001	1.424	1.212	1.673	0.000

Each QOL variable was analyzed separtely in the model, adjusting for clinical stage, PS, tumor location, and smoking index.
HR measures correspond to 10-point increments in QLQ-C30 scores.
Abbreviations are the same as in Table 2.
Significant values are in bold.

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Table 3 Multivariate analysis QOL scores for LRC, DMFS, and OS.

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