Table 2 Insulin tolerance test.

From: Hypoglycemia induces vascular endothelial dysfunction in subjects with normal glucose tolerance

 

Baseline

Hypoglycemia†

P

sBP (mmHg)

117.9 ± 16.3

123.3 ± 17.4

0.009

dBP (mmHg)

69.4 ± 16.0

71.1 ± 11.4

0.227

HR (bpm)

63.9 ± 9.3

67.0 ± 9.8

0.002

PG (mg/dL)

86.4 ± 7.5

33.6 ± 9.5

 < 0.001

ACTH (pg/mL)

23.0 ± 16.1

103.3 ± 70.9

 < 0.001

Cortisol (μg/dL)

6.9 ± 3.4

13.8 ± 6.2

 < 0.001

GH (ng/mL)

0.66 ± 1.46

7.5 ± 9.4

 < 0.001

Adrenaline (pg/mL)

27.2 ± 12.8

524.4 ± 345.7

0.001

Noradrenaline (pg/mL)

269.0 ± 70.6

530.9 ± 339.0

0.001

dopamine (pg/mL)

9.6 ± 1.9

13.2 ± 2.6

0.003

RHI

2.24 ± 0.51

1.71 ± 0.44

 < 0.001

  1. Data are mean ± standard deviation. P values by Wilcoxon signed-rank test.
  2. sBP, systolic blood pressure; dBP, diastolic blood pressure; HR, heart rate. PG, plasma glucose; GH, growth hormone; ACTH, adrenocorticotropic hormone.
  3. †sBP, dBP, HR and RHI values at 120 min after insulin administration; PG, adrenaline, noradrenaline and dopamine values at hypoglycemia; ACTH, cortisol and GH values at peak during insulin tolerance test.
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