Figure 7 | Scientific Reports

Figure 7

From: A gene signature consisting of ubiquitin ligases and deubiquitinating enzymes of SKP2 is associated with clinical outcome in breast cancer

Figure 7

Comparison of the number of positive lymph nodes per patient among the SKP2 ubiquitination groups. Analyses were performed on the data set in aggregate (n = 2004) and on three major subtypes separately: luminal (n = 1542), HER2 (n = 127), and TNBC (n = 299). Subtypes are defined as in Fig. 2. Negative binomial regression was used to model count data. The means and variances of the counts of positive lymph nodes for each BC subtype is as follows: All: μ = 2.00; σ2 = 16.84. Luminal: μ = 1.80; σ2 = 14.52. HER2: μ = 3.70; σ2 = 37.77. TNBC: μ = 2.27; σ2 = 16.95.

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