Table 1 A summary of our SKP2 ubiquitination signature.

From: A gene signature consisting of ubiquitin ligases and deubiquitinating enzymes of SKP2 is associated with clinical outcome in breast cancer

SKP2 ubiquitination signature group

FZR1 copy number vs USP10/USP13 copy number

Expected SKP2 protein levels

Expected p27 protein levels

High

FZR1 > USP10/USP13

Low

High

Intermediate

FZR1 = USP10/USP13

Intermediate

Intermediate

Low

FZR1 < USP10/USP13

High

Low

Back to article page