Figure 1

Schematic representation of the cleaved hMPV fusion protein. FP fusion peptide, HRA heptad repeat A, HRB heptad repeat B, TM transmembrane domain, CT cytoplasmic tail. The approximate location of a conserved RGD motif (residues 329–331) is indicated as a magenta box. Arrows indicate the three N-linked glycosylation sites. The location of two disulfide bonds that connect the F1 and F2 protein subunits are shown as S–S.